As a long-time running medical drama, Grey’s Anatomy has the unique ability to debut many aspiring actors and actresses before they reach their peak. With an impressive thirteen seasons under its belt, C-list stars are constantly popping up and trying to make their claim to fame on the show. After taking a look back through the seasons of the Shonda Rhimes directed show, it’s clear that many actors who played a small role in Grey’s Anatomy actually ended up on some of Rhime’s later series! To learn more, we have compiled a list of the 15 celebrities you most likely forgot had guest-starred on an episode or two of Grey’s Anatomy:
15. Jesse Plemons
Months after making his big debut on football drama Friday Night Lights, Jesse Plemons appeared on Grey’s Anatomy in a 2006 episode. He starred as Jake Button and had a brain tumor caused by a unique medical condition called lionitis which made the actor almost unrecognizable. In the episode, he died during the resection of the tumor.
