General Hospital Spoilers For The Week (March 21, 2022)

© XJJohnson/

Calling all General Hospital (GH) fans! What’s set to unfold in the land of Port Charles next week?! Nina will connect the dots, while Sonny gets an unexpected call. Also, Epiphany and TJ will work together to treat a fellow colleague. Learn about these storylines and others in the below GH spoilers for the week of March 21st, 2022.

Want soap spoilers delivered to your inbox every week? Sign up for Fame10’s weekly soap opera spoilers newsletter.

9. The Puzzle Pieces Come Together

GH spoilers for the week of March 21st indicate that Nina will connect some dots. What’s this all about? She’ll have a run-in with Harmony days before, so could this be about Willow? Looks like an interesting storyline is set to unfold. As the week progresses, Nina will head to Charlie’s to talk to Phyllis, but run into Sonny. Lastly, Harmony will pick Alexis’s brain over something.

© XJJohnson/

8. Sonny’s Unexpected Call

Speaking of Sonny, GH spoilers question how Mr. Corinthos will react when he gets an unexpected call. In potentially related teasers, Michael will land in some serious hot water. Will he reach out to his dad for help? In other news, Ms. Wu is looking for a meeting with Sonny, and Curtis will also reach out at some point to talk to Port Charles’s #1 mob boss.

© XJJohnson/

7. TJ And Epiphany Work Together

Over at the hospital, GH spoilers suggest that Epiphany and TJ’s professionalism will be tested when they work together to treat a co-worker. Who lands in the hospital, and will they end up being okay? In other news, as the days go by, TJ will see something that shakes him to the core.

Love GH? Share all of your GH opinions and join the discussion on our GH Facebook Page.

© XJJohnson/

6. Alexis’s World

GH spoilers state that Alexis will be given a “juicy tip” on a story. Given that she wants The Invader to be a trusted news source in the little town, will she jump “all in” when temptation arises for a story that might be sensational? In other news, Deception will go public, but will everything unfold the way everyone hopes?

© XJJohnson/

5. Curtis And Portia Reach A Milestone

Some feel-good GH spoilers for the week of March 21st, as Portia and Curtis will mark a major milestone in their romance! As the days go by, Drew will share some news with Curtis and wonder, “what’s next?” Lastly, Taggert and Portia will reach out to Trina, as they continue to worry about their daughter’s state, considering all that’s happened recently.

© Jill Johnson/

4. Dante Deals With A “Situation”

Across town, GH spoilers for this week hint that Dante will deal with a sensitive situation that arises. As the days go by, he will come together with Sam and Anna Devane to compare some notes. By the time the weekend hits, Mr. Falconeri will reach out to Jordan to discuss a case.

© ChrisD/

3. Spencer’s A Free Man!

Time flies, huh? GH spoilers reveal that Spencer’s time at Spring Ridge will wind to a close soon, and Nikolas and Laura will want to organize something special for him. As the days go by, Nik will decide to plan a family dinner. Will this event include both his mom and his Uncle Victor?

© XJJohnson/

2. Ava Keeps Her Eye On Victor

GH spoilers suggest that as Victor regroups this week, Ava will keep a close eye on him. In other Cassadine news, Spencer will be floored when Nik and his wife decide to bluntly ask Victor what he’s up to. The best way to get honesty is to flat-out ask what you want to be answered. But will their uncle reveal his hand?

© XJJohnson/

1. More Spoilers!

GH spoilers imply that Ava will be a busy bee this week, as she won’t only be dealing with Cassadine drama, but baby daddy drama, too. She and Sonny will come together to decide on co-parenting Avery during a tricky situation. Lastly, Finn won’t feel overly optimistic but Chase will encourage him to hang in there!

© Howard Wise/

Dorathy Gass

Dorathy Gass

Dorathy Gass is an avid fan of daytime drama and has been watching Days of Our Lives, General Hospital, and Young and the Restless for over two decades now. As a full-time freelance writer, she gets to combine her love of soap operas and writing through her Fame 10 articles. Also a mother of two busy girls and a mommy blogger, she's been published multiple times over in Huffington Post Parents and Scary Mommy.